Fig. 6.

DNMTs and TETs expression levels in HD and CLL B cells. A DNMTs and TETs mRNA levels in HD B cells (n = 9) compared with CLL samples (n = 9). Data are expressed as relative quantification using comparative Ct method (2^–ΔΔCt) and normalized to the expression value of the human embryonic kidney 293 cell line (HEK293) set as 1. Data are reported as mean ± SEM. Comparisons were performed with Unpaired t test. **P < 0.01. B DNMT1 mRNA expression correlated to CAT mRNA expression (n = 9). DNMTs DNA methyl transferases 1, TETs ten-eleven translocation, HD healthy donor, CLL chronic lymphocytic leukemia