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. 2022 Sep 16;12:388. doi: 10.1038/s41398-022-02155-x

Table. 6.

Mediation between aerobic fitness, hippocampal formation subfield volumes, and Verbal Learning and Memory Test long-term memory scores.

Mediator ACME CIlow CIhigh p pfdr
Tail-r 0.037 −0.089 0.190 0.520 0.776
Tail-l 0.043 −0.080 0.202 0.530 0.776
Subiculum-head-r −0.060 −0.233 0.068 0.366 0.776
Subiculum-head-l −0.128 −0.316 −0.009 0.020* 0.640
Subiculum-body-r 0.028 −0.043 0.133 0.486 0.776
Subiculum-body-l 0.027 −0.061 0.148 0.546 0.776
Presubiculum-head-r −0.021 −0.207 0.145 0.790 0.832
Presubiculum-head-l −0.051 −0.247 0.106 0.538 0.776
Parasubiculum-r 0.055 −0.057 0.198 0.346 0.776
Parasubiculum-l −0.025 −0.132 0.047 0.558 0.776
ML-head-r −0.071 −0.253 0.080 0.342 0.776
ML-head-l −0.107 −0.297 0.034 0.130 0.776
HATA-r 0.052 −0.088 0.223 0.484 0.776
HATA-l −0.023 −0.146 0.094 0.682 0.832
GCMLDG-head-r −0.115 −0.308 0.052 0.186 0.776
GCMLDG-head-l −0.041 −0.205 0.101 0.548 0.776
GCMLDG-body-r 0.062 −0.057 0.217 0.322 0.776
GCMLDG-body-l 0.141 0.007 0.320 0.040* 0.640
Fissure-r 0.014 −0.097 0.144 0.806 0.832
Fissure-l 0.028 −0.084 0.156 0.586 0.781
CA4-head-r −0.101 −0.319 0.090 0.280 0.776
CA4-head-l −0.020 −0.192 0.127 0.768 0.832
CA4-body-r 0.070 −0.065 0.248 0.330 0.776
CA4-body-l 0.130 −0.026 0.331 0.122 0.776
CA3-head-r −0.107 −0.298 0.069 0.216 0.776
CA3-head-l 0.016 −0.099 0.150 0.780 0.832
CA3-body-r −0.023 −0.161 0.073 0.704 0.832
CA3-body-l 0.023 −0.106 0.166 0.702 0.832
CA1-head-r −0.124 −0.328 0.037 0.126 0.776
CA1-head-l −0.086 −0.273 0.067 0.278 0.776
CA1-body-r −0.055 −0.202 0.060 0.352 0.776
CA1-body-l −0.007 −0.155 0.136 0.882 0.882

Note. The 32 mediation analyses with n = 47 are listed. The hippocampal formation subfields that were associated with aerobic fitness were used as mediators between aerobic fitness and long-term memory performance.

Significant p values (<0.05) are written in bold and marked with an asterisk.

ACME average causal mediation effect, CIlow lower confidence interval, CIhigh higher confidence interval, p uncorrected p value, pfdr fdr-corrected p value.