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. 2022 Sep 16;12:15566. doi: 10.1038/s41598-022-18805-5

Table 1.

Demographics, cognitive function and biological measures in patients defined as stable MCI and converters to AD.

sMCI (N = 357) cAD (N = 321) t/x2 p value Effect size
Mean (SD) Mean (SD)
Demographics
Age 73.1 (7.45) 73.9 (7.11) 1.35 0.176 0.10
Gender (%F) 41.2 38.9 0.352 0.553 0.02
Cognitive function
RAVLT-Im 36.9 (10.5) 29.3 (7.7) 10.56 < 0.001 0.81
RAVLT-delay 4.88 (3.93) 2.05 (2.67) 10.87 < 0.001 0.84
RAVLT-recog 11.26 (3.16) 9.42 (3.56) 7.13 < 0.001 0.55
TMTA 39.2 (15.6) 44.7 (21.5) 3.90 < 0.001 0.30
TMTB 108.1 (56.9) 133.8 (73.9) 5.10 < 0.001 0.39
CFT animals 17.8 (5.17) 15.8 (4.75) 5.13 < 0.001 0.39
GDS: mean (SD) 1.71 (1.44) 1.65 (1.38) 0.53 0.596 0.04
ANART Total errors 12.9 (9.3) 13.3 (9.6) 0.61 0.539 0.05
Biological measures
Hippocampus volume 0.00451 (7.610-4) 0.00398 (6.810-4) 9.64 < 0.001 0.74
APOE (%positive) 42.3 64.2 32.45 < 0.001 0.22

sMCI stable Mild Cognitive Impairment, cAD converted to Alzheimer’s disease, RAVLT Rey Auditory Verbal Learning Test, TMT Trail Making Test, CTF Category Fluency Test, GDS Geriatric Depression Scale, ANART American National Reading Test.