. 2022 Sep 16;12:15568. doi: 10.1038/s41598-022-19579-6

Table 2.

Ugi adducts 8a–8d and 9 derived from CO-FA.


Fatty acids in CO-FA			R	Ugi adduct	Yield		Conversion efficiency (%)
Fatty acids in CO-FA			R	Ugi adduct	mg	Ratio (wt%)	Conversion efficiency (%)
(R)-Ricinoleic acid	18:1^Δ9	90%^a	(R,Z)-12-Hydroxy-9-octadecenoyl	8a	143.44^b	84	44
(R)-Ricinoleic acid	18:1^Δ9	90%^a	-	9	4.20^b	84	1.4
Dimeric (R)-ricinoleic acid			(R,Z)-12-(((R,Z)-12-Hydroxy-9-octadecenoyl)oxy)-9-octadecenoyl	8b	5.29^b	3	1.1
Oleic acid	18:1^Δ9	3%^a	(Z)-9-Octadecenoyl	8c	11.04^c	6	3.5
Linoleic acid	18:2^Δ9,12	4%^a	(Z,Z)-9,12-Octadecadienoyl	8d	11.00^c	6	3.5
Total					174.97	100	54

^aData (wt%) from Ref.³³. ^bIsolated yield. ^cEstimated yield from ¹H NMR analysis of a mixture of 8c and 8d.