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. 2022 Sep 16;12:389. doi: 10.1038/s41398-022-02144-0

Table 3.

Statistics of diagnosis trajectory analysis using the set of HIRA.

Features Frequency

Trajectorya

 = the first and followed nodes linked via edges

No. of trajectories 405

Node

 = Diagnosed patients as a disease i

Total type of diagnosis 604
 The 1st diagnosis 170
 Patients in the 1st diagnosis 1,023,171
 Fatal outcomes of diagnosis 2 134

Edge (Directed acyclic edge)

 = Sequence between diagnosis i and j

(FDR < 0.1)b

Subsequent diagnoses after the 1st diagnosis 80,316
Mean of steps diagnoses in a trajectory 3.24 ± 1.12

aThe trajectory consists of the first node, representing a set of patients diagnosed with disease i, succeeding nodes are connected via a directed acyclic edge, representing subsequent diagnoses that occur more frequently than randomly.

bAll the presented edges were statistically significant (Relative association (RA) for the co-occurrence of diagnosis i and j > 1 and FDR of the binomial test for the co-diagnosis of diagnosis i and j < 0.1; FDR of the binomial test for the sequential directionality of diagnosis dates <0.1). The details of the diagnosis trajectory model are presented on the following website (https://www.youtube.com/watch?v=jJMds31-e2g).

Bold characters to emphasize the numbers of the table.