Table 2.
Subject details summarized by highest grade of CIPN reported.
| Max Grade CIPN |
Median NfL | Mean age | Time to max grade CIPN | Treatment duration | Cycles of chemo | Cumulative Pac dose reduction | n |
|---|---|---|---|---|---|---|---|
| (pg/mL) | (years/SD) | (days) | (days) | (#) | (%) | ||
| 0 | 42 | 62.4 (9.7) | – | 199 | 4.9 | 5 | 34 |
| 1 | 48 | 61.5 (9.3) | 44 | 183 | 5.3 | 10 | 20 |
| 2 | 153 | 65.5 (7.6) | 64 | 215 | 5.5 | 17 | 23 |
| 3 | 95 | 67 (7.1) | 117 | 222 | 5.6 | 15 | 11 |
Values reflect median NfL change, average age in years (SD), average of time to report of highest grade CIPN, time on study, reduction in cumulative dose of paclitaxel. Chemo: Chemotherapy; Pac: Paclitaxel.