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. Author manuscript; available in PMC: 2023 Sep 15.
Published in final edited form as: Mol Cell. 2022 Jul 15:S1097-2765(22)00612-8. doi: 10.1016/j.molcel.2022.06.029

Figure 7. Lack of USF recruitment impacts residence time of colocalized factors.

Figure 7.

(A) Micrograph showing particle trajectories of HALO-SMAD3 in WT CH12 B cells. Colors represent different tracks. Bar = 1 μm. (B) Survival probability (%) of HALO-SMAD3 molecules in WT (blue) or 4KO (red) CH12 B cells. The data was fitted to power-law or biexponential curves respectively. (C) Box plot showing binding time distribution (in seconds) of HALO-SMAD3 molecules expressed in WT or 4KO cells. (D) Pie charts showing percentage of the different diffusive states of SMAD3 (left) or SMAD7 (right) displaying residence times of 5-10” (white), 10-20” (grey) or > 20” (yellow). Upper pie charts represent data from WT cells, lower from 4KO.