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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: Trends Parasitol. 2022 Aug 20:S1471-4922(22)00179-9. doi: 10.1016/j.pt.2022.08.002

Table 1.

Ortholog group of some enzymes involved in apicoplast metabolism

Abbreviation Protein name Pathway Ortholog group*
Fd Ferredoxin several OG6_106507
FNR Ferredoxin-NADP+ reductase several OG6_107528
DXPS 1-deoxy-D-xylulose-5-phosphate synthase MEP OG6_104068
DXPR D-xylulose 5-phosphate reductoisomerase MEP OG6_105665
IspD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase MEP OG6_103820
IspE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase MEP OG6_492256
IspF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase MEP OG6_105913
IspG 4-hydroxy--3-methylbut-2-en-1-yl diphosphate synthase MEP OG6_105784
IspH 1-deoxy 4-hydroxy-3-methylbut-2-enyl diphosphate reductase MEP OG6_105777
LipA Lipoate synthase FASII OG6_100980
LipB Lipoate (octanoyl)transferase FASII OG6_101396
MiaA tRNA isopentenyltransferase tRNA mod. OG6_100923
MiaB tRNA-2-methylthio-N6-dimethylallyladenosine synthase tRNA mod. OG6_101475
GAPDH Glyceraldehyde 3-phosphate dehydrogenase NADH generation OG6_100218
NTH NAD(P)+ transhydrogenase transport OG6_101345