Table 3.
Immunohistochemical staining and NTRK fusions of the cohort.
| Case | Immunohistochemical stains | NTRK fusion | |||
|---|---|---|---|---|---|
| Pan-TRK | S100 | CD34 | Desmin | ||
| 1 | ND | ND | ND | 0 | C16orf72∷NTRK1 |
| 2 | 3 (D, C) | 1 (F) | POS | 0 | TPM3∷NTRK1 |
| 3 | 3 (D, C) | ND | ND | 0 | TPR∷NTRK1 |
| 4 | 2 (D, C) | 0 | ND | 0 | TPR∷NTRK1 |
| 5 | ND | POS | POS | 0 | TPM3∷NTRK1 |
| 6 | 3 (D, C) | 2 (MF) | 3 (MF) | 0 | TPR∷NTRK1 |
| 7 | 1 (F, C) | 2 (D) | 2 (MF) | 0 | EML4∷NTRK3 |
| 8 | 2 (D, C) | 0 | 0 | 0 | TFG∷NTRK3 |
| 9 | 1 (P, N) | 2 (MF) | 0 | 0 | Failed QC |
| 10 | 2 (D, C) | 3 (MF) | 2 (MF) | 0 | SPECC1L∷NTRK3 |
| 11 | 3 (D, C) | 1 (MF) | 3 (MF) | 0 | TPM3∷NTRK1 |
| 12 | 2 (D, C) | 3 (MF) | 0 | 0 | Insufficient tissue |
| 13 | 2 (D, C) | 3 (MF) | 0 | 0 | TPR∷NTRK1 |
| 14 | 3 (D, C) | 2 (MF) | ND | 0 | IRF2BP2∷NTRK1 |
| 15 | 3 (D, C) | 2 (MF) | ND | ND | TPM3∷NTRK1 |
0 = negative; 1 = weak; 2= moderate; 3= strong; F = focal; MF = multifocal; P = patchy; D = diffuse; C = cytoplasmic; N = nuclear; ND = not done; POS = positive by report (slides not available for review)