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. Author manuscript; available in PMC: 2023 Oct 1.
Published in final edited form as: Am J Surg Pathol. 2022 Jun 20:10.1097/PAS.0000000000001929. doi: 10.1097/PAS.0000000000001929

Table 6.

Comparison of clinicopathologic features of NTRK-rearranged uterine sarcomas with NTRK1 and NTRK3 fusions.

NTRK1 (n=31) NTRK3 (n=10) Univariate p
Mean age (years) (SD) 37.0 (11.6) 37.6 (14.8) 0.89
Stage 0.081
 IA 13 (52%) 1 (11%)
 IB 10 (40%) 7 (78%)
 IIB 2 (8%) 1 (11%)
Mean size (cm) (SD) 5.6 (3.4) 10.5 (6.1) 0.004
Mean mitotic activity per 10 HPFs (SD) 7.3 (8.2) 13.3 (15.8) 0.13
Lymphovascular invasion 1.0
 Present 3 (12%) 1 (14%)
 Absent 23 (88%) 6 (86%)
Necrosis 1.0
 Present 10 (34%) 4 (40%)
 Absent 19 (66%) 6 (60%)
Recurrence 0.044
 Yes 6 (25%) 6 (67%)
 No 18 (75%) 3 (33%)
Death from disease 0.30
 Yes 2 (8%) 2 (78%)
 No 22 (92%) 7 (22%)