Figure 3.

Yun interacts with and stabilizes Tkv

(A) Some endogenous Yun puncta (red) co-localize with endogenous Tkv (green) (yellow arrowheads). Yun and Tkv channels are shown separately in black and white.

(B) Endogenous Tkv associates with both overexpressed and endogenous Yun by coimmunoprecipitation.

(C) Tkv (red) in control GSCs (white arrowheads). Tkv channel is showed separately in black and white.

(D) The levels of Tkv (red) are dramatically reduced in nos > yun^shmiR germarium (white arrowheads).

(E) Quantification of Tkv fluorescence in control and nos > yun^shmiR GSCs. Mean ± SEM is shown. n = 10. ^∗∗∗∗p < 0.0001. Scale bars: 10 μm.