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. 2022 Aug 30;149(16):dev200398. doi: 10.1242/dev.200398

Fig. 3.

Fig. 3.

Model of eRNA-mediated control of transcriptional condensate formation. Early in transcription initiation, nascent eRNAs transcribed from enhancers stimulate the formation of transcriptional condensates via phase separation. Upon transition into transcriptional elongation, the production of long genic RNAs results in electrostatic repulsion that stimulates dissolution of the transcriptional condensates.