Skip to main content
. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Alzheimers Dement. 2022 Mar 17;19(1):169–180. doi: 10.1002/alz.12656

Figure 4: Associations between LC intensityr and memory performance.

Figure 4:

Note: A) Differences between carriers (n=26) and noncarriers (n=27) in the association between LC intensityr and memory (left: learning, right: delayed recall). Shaded regions show the 95% confidence interval. B) Quasi-Bayesian Monte Carlo Mediation results: vertex-wise analyses showing which tau regions (FTP SUVr, PVC) mediated the relationship between LC intensityr and memory in the carriers (n=26). Analyses were corrected for multiple comparisons using a cluster-wise correction at p<0.01. The scale bar reflects the magnitude of the probability of the indirect (mediation) effect (expressed in -log10(p-value); yellow: greater; red: smaller). C) ROI-based analyses (precuneus) confirming that precuneus FTP (SUVr, PVC) mediates the relationship between LC intensityr and memory. Abbreviations: WLL= word list learning, L=left, R=right