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Schematic of αCD3-αEGFR-PD-1-OX40L GEMINI-Exos for targeted cancer immunotherapy
HA, hemagglutinin; PD-1, programmed death 1; OX40L, OX40 ligand; αCD3, anti-CD3; αEGFR, anti-EGFR; scFv, single-chain variable fragment; PDGFR TMD, transmembrane domain of human platelet-derived growth factor receptor; PD-L1/L2, programmed death-ligand 1/ligand 2.
