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The influx of CD11b+Ly6CHi monocytes/macrophages during wound healing under normal and diabetic conditions
During normal wound healing, monocyte-derived Ly6CHi macrophages are present within 48 h of injury and rapidly transition to Ly6CLo macrophages, releasing pro-healing mediators at the wound site. In diabetic wounds, transition of Ly6CHi to Ly6CLo macrophages is delayed, leading to a second influx of Ly6CHi monocyte/macrophages during the reparative phase. Created with BioRender.
