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Knockout of mdig enhances invasive migration of the MDA-MB-231 cells and affects the expression of genes associated with invasion and EMT
(A) Cell morphology of the WT and KO cells.
(B)Trans-well invasion assay of the WT and KO cells. WT clones 2, 3 and 4, and KO clones 6, 7 and 8 were shown. Bottom panel shows relative numbers of invasive cells of the WT and KO cells. Data are represented as mean ± SD.
(C) Immunoblotting of the indicated proteins between 5 WT clones and 12 KO clones.
