Table 1.
Chemical physical characterization of nanoparticles and nanoconjugates used in this work
| Sample | DLS (nm) | std (nm) | Zeta potential (mV) | std (mV) | Loading (n. VIVIT/NP) |
|---|---|---|---|---|---|
| MYTS | 22.9 | 1.4 | −49.8 | 1.5 | – |
| MYTS-VIVIT | 22.6 | 2.4 | −45.1 | 1.5 | 17.0 |
| MYTS-PEG | 26.2 | 1.6 | −49.1 | 1.8 | – |
| PMDA | 5.4 | 0.2 | −40.1 | 4.5 | – |
| PMDA-VIVIT | 5.5 | 0.2 | −29.5 | 4.2 | 0.6–1.6a |
| PMDA-PEG | 5.5 | 0.6 | −30.9 | 3.9 | – |
| HFn | 13.0 | 3.1 | −11.6 | 5.6 | – |
| HFn(VIVIT) | 13.4 | 3.0 | −10.2 | 4.4 | 38.4 |
All measurements were conducted in 10 mM ionic strength, pH 7.35.
a
The value is size-dependent (in the range 5–9 nm) calculated at a density of 1 mg/mL.