Table 3.

Demographics and Systemic Characteristics of Patients With WFS1

			Age (Year)
Clinical Manifestations	Patient Number	Percentage	Mean ± SD	Media	Range
Major clinical manifestations
DM	21	91.3%	9.6 ± 8.0	8.0	2–32
OA	23	100.0%	12.4 ± 7.4	9.0	4–33
D	9	39.1%	10.0 ± 2.8	10.0	5–15
DI	5	21.7%	16.6 ± 14.1	13.0	5–41
Other system manifestations
Urinary tract dysfunction	9	39.1%	18.7 ± 12.9	16.0	6–41
Balance impairment	3	13.0%	6.7 ± 0.6	7.0	6–7
Olfactory decline	2	8.7%	/	33.0	24, 42
Psychiatric symptoms	2	8.7%	/	11.5	7, 16
Died	1	4.3%	/	13.0	/
Fecal incontinence	1	4.3%	/	16.0	/
Memory deterioration	1	4.3%	/	14.0	/
Tetralogy of Fallot	1	4.3%	/	0.5	/

SD, standard deviation.