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. 2022 Sep 17;53:101651. doi: 10.1016/j.eclinm.2022.101651

Table 2.

Linear regression models for univariate associations, predictors and concomitant factors of FACIT fatigue scores.

Univariate
Model 1: Predictors (n = 907)
Model 2: Concomitant factors (n = 615)
Characteristic B 95% CI Std. beta p B 95% CI Std. beta p B 95% CI Std. beta p
Sociodemographic Gender < 0.001 0.11 < 0.001
Female
Male 3.48 2.17, 4.80 0.17 2.37 1.11, 3.63
Age [years] 0.07 0.03, 0.11 0.11 < 0.001 0.08 0.04, 0.12 0.11 < 0.001
Education 0.683
< 12 years
≥12 years −0.28 −1.62, 1.06 −0.01
Potential predictors Any neuropsychiatric disease −5.76 −7.23, −4.28 −0.24 < 0.001 −1.98 −3.72, −0.24 −0.08 0.026
Depression disorder −8.72 −10.82, −6.62 −0.26 < 0.001 −5.03 −7.51, −2.56 −0.15 < 0.001
Anxiety disorder −5.21 −8.81, −1.61 −0.09 0.005
Sleep apnoea −3.34 −6.51, −0.18 −0.07 0.038 −2.65 −5.65, 0.34 −0.05 0.082
Chronic kidney disease 0.16 −5.56, 5.88 0.00 0.956
Cardiovascular disease 0.21 −1.25, 1.68 0.01 0.773
Tumour disease −1.79 −7.14, 3.56 −0.02 0.511
Number of acute COVID symptoms −0.87 −1.01, −0.73 −0.36 < 0.001 −0.76 −0.91, −0.62 −0.32 < 0.001
Treatment setting 0.777
Home isolation 0.02
General ward −0.33 −3.44, 2.78 −0.01
Intensive care −1.87 −7.23, 3.49 −0.02
Concomitant factors Time since diagnosis [days] 0.03 0.02, 0.04 0.16 < 0.001 0.01 0.00, 0.01 0.04 0.062
Anaemia 1.39 −1.10, 3.88 0.04 0.274
C−reactive protein [mg/l] −0.25 −0.45, −0.05 −0.08 0.013
Cognition (MoCA) −0.04 −0.30, 0.23 −0.01 0.784
Depression (PHQ-8) −1.95 −2.03, −1.86 −0.83 < 0.001 −1.61 −1.74, −1.47 −0.69 < 0.001
Anxiety (GAD-7) −1.78 −1.91, −1.65 −0.66 < 0.001
Sleep (PSQI) −1.71 −1.86, −1.55 −0.65 < 0.001 −0.51 −0.66, −0.35 −0.19 < 0.001