Table 1.
WT (25) |
NGF-OE (25) |
|||
---|---|---|---|---|
Phasic | Multiple firing | Phasic | Multiple firing | |
| ||||
Cell type | 60 % (15/25) | 40 % (10/25) | 72 % (18/25) | 28 % (7/25) |
RMP (mV) | −60±3 (8) | −58±3 (7) | −58±1 (10) | −56±1 (4) |
Input R (MΩ) | 116±20 (15) | 201±31 (10)* | 142±18 (18) | 161±41 (7) |
AHP amplitude (mV) | 10±1 (15) | 6±1 (9) | 8±1 (17) | 7±1 (7) |
AHP duration (ms) | 202±60 (15) | 26±10 (9)* | 213±51 (17) | 65±26 (7) |
MPG major pelvic ganglion, WT wild-type, NGF-OE nerve growth factor overexpressing, RMP resting membrane potential, R resistance, AHP. afterhyperpolarization
p≤0.05 (compared to phasic-firing MPG neurons in WT mice)