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. 2022 Aug 18;14(8):e28147. doi: 10.7759/cureus.28147

Table 3. Minimally invasive treatment options for sialolithiasis.

ESWL: Extracorporeal Shockwave Lithotripsy; FDA: Food and Drug Administration

  Sialendoscopy Sialendoscopy with laser lithotripsy Extracorporeal shockwave lithotripsy (ESWL)
Best uses <5mm stones Stones that are free-floating within duct 5-7mm stones Any sized stone, although most effective for <7mm stones
Advantages Minimally invasive Direct, high-definition intra-ductal visualization Variety of extraction instruments available Stones can be extracted intact Direct, high-definition intra-ductal visualization Ability to remove larger sized stones while avoiding more invasive surgical operations Easy to perform, in-office procedure Repeatable Very well-tolerated Stone fragments may pass spontaneously, thereby avoiding operating room and anesthesia
Disadvantages   Injuries to surrounding soft tissues Possibility of incomplete stone clearance leading to recurrence Injuries to surrounding soft tissues
Success rate >80% 81-100% 26-81%
Complication rate 3% 13% N/A
Possible complications Ductal strictures Perforations Ranula formation Lingual, facial nerve injuries Infection Bleeding Ductal strictures Perforations Thermal injury to nerves and vessels (may be avoided with continuous cold saline rinsing)  
Comments   Thermal injuries may be minimized with continuous saline rinsing and avoiding the duct wall with the laser Ductal stenosis can be prevented with stent placement Sialendoscopy often performed following ESWL for complete stone fragment removal Not FDA approved in United States