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CpG-C hinders the development of CT26 surface-hepatic metastases and reduces liver weight. CpG-C (100 µg/mouse) or PBS (control) were injected twice, 24 h prior and 24 h following 20,000 CT26 tumor cell inoculation. CpG-C treatment significantly reduced number of metastases (a), and liver weight (b). The average weight of livers without metastases is approximately 1 g. Data are expressed as mean + SEM. * indicates a significant difference from PBS control levels
