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IC50 Values of Compounds 1 and 8 in G9a and GLP SAHH-Coupled Enzymatic Assaysa
| compd 1 | compd 8 | UNC0642 | |
|---|---|---|---|
| IC50 for G9a (nM) | 3100 ± 260 | 100 ± 6 | 220 ± 14 |
| IC50 for GLP (nM) | 1800 ± 240 | 140 ± 5 | 180 ± 21 |
IC50 values are reported as the mean ± SD from four independent experiments.
