Table 4. Median value of FC and the δFC measured at 6 weeks after treatment according to drug and treatment response in patients with Crohn’s disease.
| Variable | Type of drug for RI | CR at 6 months after RI | ER at 1 year after RI | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Anti-TNF-α | Oral PRS | p-value | (+) | (−) | p-value | (+) | (−) | p-value | |
| FC (µg/g) | 473.5 | 950.4 | 0.7479 | 486.5 | 1,504.0 | 0.0025 | 373.0 | 1,500.0 | 0.0004 |
| δFC (%) | 80.0 | 52.5 | 0.3550 | 81.1 | 6.4 | 0.0049 | 84.8 | 24.8 | 0.1738 |
δFC was calculated as follows: (FC pre-treatment – FC 6 weeks post-treatment)×100/(FC pre-treatment), as a percentage.
FC: fecal calprotectin, δFC: delta FC, RI: remission induction, CR: clinical remission, ER: endoscopic remission, Anti-TNF-α: anti-tumor necrosis factor alpha, PRS: prednisolone.