Table 1.
Distribution of the 4 intrinsic subtypes within patients with Ki67 data and by Ki67 categories Abbreviations: HER2-E, HER2-Enriched Subtype; LumA, Luminal A subtype; LumB, Luminal B subtype; GR, Good response; IR, Intermediate response, PR, Poor response; Ki672wk, Ki67 at 2 weeks timepoint.
| TREATED |
CONTROLS |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Arm | All | Basal | HER2-E | LumA | LumB | All | Basal | HER2-E | LumA | LumB |
| 226 (100.0%) | 3 (1.3%) | 95 (42.1%) | 45 (19.9%) | 83 (36.7%) | 50 (100.0%) | 0 (0.0%) | 27 (54.0%) | 4 (8.0%) | 19 (38.0%) | |
| Ki67 Response Categories | ||||||||||
| GR | 70 (31·0%) | 0 (0·0%) | 15 (15·8%) | 18 (40·0%) | 37 (44·6%) | 0 (0·0%) | 0 (0·0%) | 0 (0·0%) | 0 (0·0%) | 0 (0·0%) |
| IR | 51 (22·5%) | 0 (0·0%) | 17 (16·5%) | 11 (24·4%) | 23 (27·7%) | 2 (4·0%) | 0 (0·0%) | 1 (3·80%) | 0 (0·0%) | 1 (5·3%) |
| PR | 105 (46·5%) | 3 (100%) | 63 (66·3%) | 16 (35·5%) | 23 (27·8%) | 48 (96·0%) | 0 (0·0%) | 26 (96·3%) | 4 (100%) | 18 (94·7%) |
| Chi -squared 27·69, P<0·00001 | Fisher's exact test P>0·05 | |||||||||
| Ki672wks | ||||||||||
| HIGH | 118 (52·0%) | 3 (100·0%) | 80 (84·2%) | 7 (15·6%) | 28 (33·7%) | 48 (96·0%) | 0 (0·0%) | 27 (100%) | 3 (75·0%) | 18 (94·7%) |
| LOW | 109 (48·0%) | 0 (0·0%) | 15 (15·8%) | 38 (84·4%) | 55 (66·3%) | 2 (4·0%) | 0 (0·0%) | 0 (0·0%) | 1 (25·0%) | 1 (5·30%) |
| Chi-squared 67·98, P<0·00001 | Fisher's exact test P>0·05 | |||||||||