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Mechanism of targeting CSCs by curcumin nanoformulations. A nanotechnology-based drug delivery system can improve the bioavailability and antitumor activity of curcumin and promote the targeting of curcumin to CSCs. By regulating surface markers, signaling pathways, the tumor microenvironment, EMT, and other mechanisms of CSCs, curcumin nanoformulations have shown excellent efficacy against pancreatic cancer, breast cancer, colorectal cancer, glioma, and other cancers.
