Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Sep 5;13:932286. doi: 10.3389/fendo.2022.932286

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Taub, Mahmoudzadeh, Tennessen and Sudarshan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Expression of genes affecting tubulogenesis, and cell migration. (A). The relative level of mRNA encoding for E-Cadherin (CDH1), tissue Plasminogen Activator (PLAU), Wnt1 and Chibby homolog 1 (CBY1) was determined in parallel monolayer and matrigel cultures. The relative level of the mRNA encoding for (B) E-Cadherin, (C) Plasminogen Activator, (D) WNT1, and (E) CBY1 (1) was determined in monolayer and matrigel cultures tranduced with lentiviral L2HGDH shRNA or Control TRC shRNA. (F) EGF-stimulated cell migration across PET membranes was determined in RPT cells following their transduction with lentiviral L2HGDH shRNA or Con TRC shRNA. (*) p < 0.05 relative to monolayer cultures in the same condition in panel (A); In panels (B–E), (*) p < 0.05 relative to the Con TRC monolayer culture condition; in 11F (*) p < 0.05 relative to the scr shRNA condition; (#) p < 0.05 relative to the Con TRC Matrigel Condition (E).