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. 2022 Sep 5;13:885029. doi: 10.3389/fimmu.2022.885029

Figure 3.

Figure 3

Diabetes metabolism and its immune regulation effect on periodontitis: diabetes regulates the host’s response to periodontal pathogens by changing its structure and metabolites AGE, fat factor, cytokines, bone metabolism and immune response, and participate in the immune regulation of diabetes to periodontitis microflora. PMN, polymorphonuclear neutrophil; MNP, mononuclear phagocytic cells; DC, dendritic cells; PRRs, pattern recognition receptors; TLRs, Toll-like receptors; RANK, Receptor activator of NF-κB; AGEs, advanced glycation end products; LDL, low density lipoprotein; HDL, high density lipoprotein; TC, total cholesterol.