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. 2022 Sep 15;39(11):2905–2918. doi: 10.1007/s11095-022-03378-9

Fig. 4.

Fig. 4

(i) Optical microscope image of the assembled modulated tablet with each compartment (a), Outer layer (dout = 12 mm), middle layer (dmid = 8 mm) and core (dcore = 4 mm) of the concentric cylinder (height = 4 mm). (b), Electro-magnetic droplet printing of reactive orange 16 (1 mg/ml) on solid tablet (up left) and each compartment. EMD printing parameters: print design (same shape as the BJ design, height = 0.5 mm), infill pattern (concentric), infill density (25% as default), pressure (5 kPa), open time (2 ms), cycle time (100 ms), printing speed (10 mm/s as default). (c), EMD-printed tablet compartments assembled with the blank compartments; (ii) Images of drug-loaded tablet compartments and assembled tablets taken by optical microscope. (a), out layer: blue ritonavir; middle layer: violet favipiravir; core: red HCS. (b), single compartment assembled with blank tablet compartments to visualize the color change. (c), assembled blank tablets versus drug-loaded tablets.