TABLE 4.
Changes in whole‐body protein turnover by post‐SERE hormonal status
| Post‐SERE testosterone status | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Low testosterone (n = 24, < 10.5 nmol/L) | Low testosterone (n = 44, < 10.5 nmol/L) | p‐value | |||||||
| Pre | Post | Δ | Pre | Post | Δ | Group | Time | Interaction | |
| Whole‐body protein turnover, g protein·kg−1·day−1 | |||||||||
| Protein synthesis | 6.30 ± 0.99 | 5.63 ± 1.32 | −0.68 ± 1.29 | 7.06 ± 1.27 | 6.59 ± 1.75 | −0.51 ± 2.21 | 0.0019 | 0.025 | 0.69 |
| Protein breakdown | 5.08 ± 1.33 | 6.14 ± 1.46 | 1.10 ± 1.47 | 6.09 ± 1.56 | 7.27 ± 2.06 | 1.15 ± 2.15 | 0.0036 | < 0.0001 | 0.85 |
| Net protein balance | 1.22 ± 0.89 | −0.51 ± 0.31 | −1.78 ± 0.84 | 0.96 ± 1.30 | −0.68 ± 0.45 | −1.66 ± 1.21 | 0.23 | < 0.0001 | 0.74 |
| Flux | 1.21 ± 0.20 | 0.98 ± 0.23 | −0.23 ± 0.22 | 1.36 ± 0.19 | 1.16 ± 0.33 | −0.20 ± 0.36 | 0.0020 | < 0.0001 | 0.66 |
Note: Mean ± standard deviation. Linear mixed models were used to assess the effects of testosterone status group, time, and their interaction on outcome measures. If a significant interaction effect was observed, post hoc comparisons were adjusted for multiple comparisons using the Bonferroni correction.