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. 2022 Sep 19;23:253. doi: 10.1186/s12931-022-02139-x

Table 2.

Logistic regression analysis of serum parameters and severity score for predicting 30-day mortality and ICU admission

Variables Prediction of mortality Prediction of ICU admission
Univariate Multivariate Univariate Multivariate
Odds ratio (95% CI) P value Odds ratio (95% CI) P value Odds ratio (95% CI) P value Odds ratio (95% CI) P value
Age 1.048 (1.026–1.072)  < 0.001 1.032 (1.000–1.069) 0.064 1.040 (1.023–1.059)  < 0.001 1.022 (0.995–1.052) 0.117
Gender 1.702 (0.786–3.993) 0.194 – – 2.327 (1.179–4.943) 0.020 1.655 (0.585–5.064) 0.354
NMI (pg/ml) 1.005 (1.003–1.007)  < 0.001 1.005 (1.003–1.008)  < 0.001 1.010 (1.007–1.014)  < 0.001 1.008 (1.004–1.011)  < 0.001
PCT (ng/ml) 1.037 (1.019–1.059)  < 0.001 0.969 (0.928–1.003) 0.105 1.121 (1.070–1.198)  < 0.001 1.058 (1.013–1.116) 0.019
CRP (mg/l) 1.012 (1.008–1.017)  < 0.001 1.008 (1.001–1.016) 0.026 1.011 (1.008–1.015)  < 0.001 1.000 (0.993–1.007) 0.964
WBC (10^9/l) 1.037 (1.006–1.068) 0.018 1.201 (0.667–1.716) 0.371 1.065 (1.032–1.105)  < 0.001 1.035 (0.758–1.444) 0.829
Neutrophils (10^9/l) 1.058 (1.02–1.097) 0.002 0.780 (0.492–1.526) 0.327 1.088 (1.049- 1.133)  < 0.001 1.013 (0.653–1.536) 0.951
NCP (%) 1.111 (1.066–1.165)  < 0.001 1.080 (0.982–1.197) 0.121 1.083 (1.049–1.121)  < 0.001 1.024 (0.948–1.116) 0.562
PSI 3.117 (2.290–4.434)  < 0.001 0.889 (0.468–1.705) 0.719 2.809 (2.181–3.709)  < 0.001 1.190 (0.664–2.162) 0.560
CURB65 score 3.336 (2.474–4.682)  < 0.001 2.882 (1.529–5.647) 0.001 3.000 (2.323–3.972)  < 0.001 2.051 (1.167–3.664) 0.013

Gender is categorical variables (male set as 1 and female set as 0). Other indicators are continuous variables. The PSI and CURB65 score are ordered categorical variable that calculated as continuous variables (values are set according to their severity grades). The bold value reflects the P value < 0.05, and there is a significant difference