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. 2022 Sep 2;27:47–60. doi: 10.1016/j.omtm.2022.08.009

Figure 2.

Figure 2

Immune response markers

(A) AAVrh74 antibody titer by ELISA immunoassay for both subjects. ELISA titers >1:50 (horizontal line) are considered positive. (B) ELISpot immunoassay values for both subjects for three AAVrh74 peptide pools and two GALGT2 peptide pools. Values ≥50 SPF/1 × 106 PBMCs (horizontal line) are considered positive. The dashed vertical steroid taper line marks the time point when gradual steroid dose tapering from the post-gene-transfer dose (of 1 mg/kg) began for each subject.