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. 2022 Sep 14;21:403–421. doi: 10.1016/j.bioactmat.2022.08.031

Fig. 8.

Fig. 8

Investigation of the osteoinductive mechanisms of SMS hydrogel. A-C) Western blot assays show the phosphorylation of MAPK pathway components in BMSCs (****p < 0.001). D) Western blot assays show the inhibitory effects of PD98059, a specific Erk1/2 inhibitor, on activating Erk1/2 (60 min) induced by SMS hydrogel. E) ALP staining of BMSCs treated with or without PD98059. F) Western blot assays show the inhibitory effects of SP600125, a specific JNK inhibitor, on activating JNK (60 min) induced by SMS hydrogel. G) ALP staining of BMSCs treated with or without SP600125.