TABLE 2.
Comparison of mild, moderate, and severe reactions.
| Characteristics | Total, n (%) | Mild, n (%) | Moderate, n (%) | Severe, n (%) | p-value | R |
|---|---|---|---|---|---|---|
| Gender | ||||||
| Male | 845 (46.87) | 263 (39.67) | 399 (51.15) | 183 (50.83) | <0.001 a | — |
| Female | 958 (53.13) | 400 (60.33) | 381 (48.85) | 177 (49.17) | ||
| Age (years) | ||||||
| <18 | 85 (4.71) | 18 (2.71) | 66 (8.46) | 1 (0.28) | <0.001 b | 0.167 |
| 18–40 | 253 (14.03) | 130 (19.61) | 104 (13.33) | 19 (5.28) | ||
| 41–64 | 692 (38.38) | 286 (43.14) | 269 (34.49) | 137 (38.06) | ||
| ≥65 | 773 (42.87) | 229 (34.54) | 341 (43.72) | 203 (56.39) | ||
| Number of suspected drugs | ||||||
| 1 | 1,221 (67.72) | 499 (75.26) | 512 (65.64) | 210 (58.33) | <0.001 b | 0.136 |
| 2 | 439 (24.35) | 126 (19.00) | 202 (25.90) | 111 (30.83) | ||
| ≥3 | 143 (7.93) | 38 (5.73) | 66 (8.46) | 39 (10.83) | ||
| Preventability | ||||||
| Unpreventable | 830 (46.03) | 422 (63.65) | 341 (43.72) | 67 (18.61) | <0.001 b | 0.299 |
| Probably preventable | 880 (48.81) | 210 (31.67) | 392 (50.26) | 278 (77.22) | ||
| Definitely preventable | 93 (5.16) | 31 (4.68) | 47 (6.03) | 15 (4.17) | ||
| Route of administration | ||||||
| Oral | 1,019 (56.52) | 340 (51.28) | 409 (52.44) | 270 (75.00) | <0.001 c | |
| Intravenous | 683 (37.88) | 281 (42.38) | 321 (41.15) | 81 (22.50) | ||
| Others | 101 (5.60) | 42 (6.33) | 50 (6.41) | 9 (2.50) |
a
Mann–Whitney U test.
b
Spearman.
c
Kruskal–Wallis H.
The R value represents Spearman’s correlation coefficient.