TABLE 4.
Methods of CCL regeneration.
| Type of strategy | Researcher | Time | Experimental model | Material | Reference |
|---|---|---|---|---|---|
| Scaffold-based | Petrovova E | 2021 | Sheep | Porous acellular PHB/CHIT-based scaffold | Petrovova et al., 2021 |
| Liu M | 2021 | Rabbit | PLCL-based tri-layered fibrous membranes | Liu et al., 2021 | |
| Cai H | 2020 | Rabbit | Injectable tissue-induced Col I hydrogel and BMSCs | Cai et al., 2020 | |
| Kosik-Kozioł A | 2019 | In vitro | Alginate, gelatin MAM, and β-TCP particles and BMSCs | Kosik-Kozioł et al., 2019 | |
| You F | 2018 | Mouse | Porous ALG/HAP hydrogel | You et al., 2018 | |
| Yang J | 2018 | Rabbit | Ica-HA/Col hydrogel and BMSCs | Yang et al., 2018 | |
| Li Z | 2018 | In vitro | PLGA, HA, and extracted bovine cartilage matrix | Li et al., 2018 | |
| Khanarian NT | 2012 | In vitro | HA and alginate hydrogel | Khanarian et al., 2012 | |
| Cheng HW | 2011 | In vitro | Collagen and BMSCs (BMSC-collagen microspheres) | Cheng et al., 2011 | |
| Jiang J | 2010 | In vitro | Agarose hydrogel and PLGA/45S5 bioactive glass | Jiang et al., 2010 | |
| Cell-based | Allan KS | 2007 | In vitro | DZCs, porous CPP, and β-GP | Allan et al., 2007 |
| Kandel R | 1999 | In vitro | Interface-relevant DZCs, Col II, and mineralization media (β-GP, PEA, and ATP) | Kandel et al., 1999 |
(a) PHB/CHIT, polyhydroxybutyrate/chitosan; (b) PLCL, poly(L-lactide-co-caprolactone); (c) Col I, type I collagen; (d) BMSCs, bone marrow mesenchymal stem cells; (e) MAM, methacrylamide; (f) β-TCP, β-tricalcium phosphate; (g), ALG/HAP: alginate/hydroxyapatite; (h) Ica-HA/Col, icariin-conjugated hyaluronic acid/collagen; (i) PLGA, polylactic-co-glycolic acid; (j) HA, hydroxyapatite; (k) DZCs, deep zone chondrocytes; (l) CPP, calcium polyphosphate; (m) β-GP, β-glycerophosphate; (n) Col II, type II collagen; (o) PEA, phosphoethanolamine; (p) ATP, adenosine triphosphate.