. 2022 Sep 12;16:100414. doi: 10.1016/j.mtbio.2022.100414

Table 4.

Pharmacokinetic parameters (mean ± SD, n = 3) after oral administration of F5, F7 and FR.

Formulation	C_max (μg/mL)	T_max (h)	AUC_0-12h (μg.h/mL)	HVD_t50%Cmax (h)	R_D (−)	Remaining MTF in tablet (%)
F5	1.3 ± 1.0^b	5.3 ± 0.6^a	1.0 ± 1.6^b	10.2 ± 1.7^a	3.2 ± 0.5^a	55.6 ± 4.9^a
F7	2.2 ± 1.0^a	4.3 ± 0.6^a	1.7 ± 1.0^a	9.4 ± 0.9^a	2.9 ± 0.3^a	17.5 ± 2.8^b
FR	2.4 ± 1.9^a	2.8 ± 0.4^b	1.5 ± 0.9^a	5.6 ± 0.6^b	1.7 ± 0.2^b	–

^a,b Means in the same column with different superscript are different at the 0.05 level of significance.