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. 2022 Sep 15;15(9):100668. doi: 10.1016/j.waojou.2022.100668

Table 2.

Compositions of human and cow's milk, modified after Crittenden et al.119 and Villa et al.81

Milk fraction Protein family Protein Human (mg/ml) Cow (mg/ml) Allergen namea Impact
Caseins Caseins α-s1-casein 0 11.6 Bos d 9 major
α-s2-casein 0 3.0 Bos d 10 minor
β-casein 2.2 9.6 Bos d 11 major
κ-casein 0.4 3.6 Bos d 12 minor
γ-casein 0 1.6 Bos d 8
Whey proteins Lipocalins β–lactoglobulin (BLG) 0 3.0 Bos d 5 major
Lysozymes α-lactalbumin (ALA) 2.2 1.2 Bos d 4 major
Transferrins lactoferrin 6.0 0.1–0.2 (evtl.minor)
Albumins serum albumin 0.4 0.4 Bos d 6 minor
Immunoglobulins immunoglobulins 0.8 0.6 Bos d 7 minor
other 0.8 0.6
a

According to the official WHO/IUIS nomenclature49 allergens are abbreviated by the first letters of the genus in Latin, followed by the first letters of the species and a number, which represents the chronological order of their discovery. Bos d: abbreviation of Bos domesticus