Table 5.
LTR7 regulatory loci linked with genes mediating transmission across synapses and protein–protein interactions at synapses
| LTR7 subfamily | Number of loci* | Number of linked genes | Number of synaptic transmission network genes** | Percent of synaptic transmission network genes |
|---|---|---|---|---|
| LTR7B | 28 | 37 | 22 | 59.5 |
| LTR7C | 24 | 38 | 19 | 50.0 |
| LTR7bc | 29 | 46 | 26 | 56.5 |
| LTR7o | 23 | 34 | 18 | 52.9 |
| LTR7d1 | 15 | 26 | 15 | 57.7 |
| LTR7d2 | 39 | 60 | 31 | 51.7 |
| LTR7u1 | 10 | 14 | 9 | 64.3 |
| LTR7u2 | 13 | 21 | 12 | 57.1 |
| LTR7up1 | 23 | 36 | 18 | 50.0 |
| LTR7up2 | 5 | 8 | 4 | 50.0 |
| LTR7Y | 11 | 18 | 10 | 55.6 |
| All LTR7 loci | 220 | 170 | 87 | 51.2 |
*Number of individual non-redundant LTR7 regulatory loci; in total, there are 235 regulatory loci linked with 170 human genes by the GREAT algorithm, including synaptic transmission networks’ genes
**Reported results are based on the Reactome database analysis of 355 synaptic transmission network genes