Table 8.
A significant majority of LTR-linked mammalian OS genes and fetal gonad’s cells marker genes are high-fidelity LTR-regulated genes
| Classification category | Number of genes | LTR-regulated | Percent | P value* |
|---|---|---|---|---|
| LTR7 target genes | 2957 | 1570 | 53.09 | |
| LTR5_Hs target genes | 935 | 486 | 51.98 | |
| LTR7 and/or LTR5_Hs target genes | 3515 | 1944 | 55.31 | |
| LTR7 target genes (at least 2 LTR7 loci per gene) | 1202 | 664 | 55.24 | 9.958E-05 |
| LTR7 and LTR5_Hs target genes | 377 | 251 | 66.58 | 9.958E-05 |
| LTR7 only target genes | 2580 | 1319 | 51.12 | 1.53E-08 |
| LTR5_Hs only target genes | 558 | 235 | 42.11 | 1.70E-13 |
| LTR7 mammalian OS target genes | 562 | 392 | 69.75 | 5.96E-19 |
| LTR7 mammalian non-OS target genes | 2395 | 1178 | 49.19 | 5.96E-19 |
| LTR5_Hs mammalian OS target genes | 126 | 92 | 73.02 | 2.85E-07 |
| LTR5_Hs mammalian non-OS target genes | 809 | 394 | 48.70 | 2.85E-07 |
|
LTR7 and/or LTR5_Hs mammalian OS target genes |
630 | 432 | 68.57 | 8.34E-14 |
|
LTR7 and/or LTR5_Hs mammalian non-OS target genes |
2885 | 1512 | 52.41 | 8.34E-14 |
| LTR7 and LTR5_Hs mammalian OS target genes | 58 | 50 | 86.21 | 0.0004271 |
|
LTR7 and LTR5_Hs mammalian non-OS target genes |
319 | 201 | 63.01 | 0.0004271 |
|
Human-specific LTR7 and/or LTR5_Hs target genes |
391 | 215 | 54.99 | |
| Fetal gonad’s cells markers hsLTR7 and/or hsLTR5_Hs target genes | 88 | 64 | 72.73 | 0.0001478 |
| Human-specific LTR7 and/or LTR5_Hs target genes (excluding fetal gonad’s cell marker genes) | 303 | 151 | 49.83 | 0.0001478 |
*P values were estimated using the 2-tail Fisher’s exact test