Table 2.
Targeted metabolomics of mouse plasma. Summary of metabolomic analyses shows the total number of metabolites analyzed in each group (On panel), the metabolites detected in mouse plasma (Detected) and the metabolites that showed a significant change (P<0.05) between WT and KO mice (KO different from WT) for male and female mice, respectively (N=8–10).
| Metabolites | On panel | Detected | KO different from WT | |
|---|---|---|---|---|
| Male | Female | |||
| Acylcarnitines | 40 | 40 | 21 | 1 |
| Amino acids | 21 | 21 | 0 | 3 |
| Biogenic amines | 21 | 16–17 | 1 | 1 |
| Glycerophospholipids | 90 | 90 | 1 | 5 |
| Sphingolipids | 15 | 15 | 0 | 0 |
| Sugars (hexose) | 1 | 1 | 0 | 0 |
| Total | 188 | 183–184 | 23 | 10 |