Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Typical PRS workflow. A normal PRS workflow involves the QC of both a base and target dataset. PRS are then calculated on the base dataset to predict the trait of interest in the target data. Validation is performed in an independent dataset to ensure a predictive and informative risk score model. This model can then be used for various clinical applications. QC, quality control; LD, linkage disequilibrium; P+T, pruning and thresholding; G/P, genotype/phenotype.
