Table 2.

Serum biochemical tests prior to, and following, treatment for 9 months

Test	Pre-treatment	Post-treatment	Significance
Hs-CRP	2.29±2.7 mg/L	0.89±0.98 mg/L	p < 0.05
Hemoglobin A1c	5.39±0.36 %	5.18±0.31 %	p < 0.05
HOMA-IR	1.58±1.32	1.23±0.63	NS
TG:HDL ratio	1.37±0.86	0.98±0.44	p < 0.05
Homocysteine	10.53±2.25 mM	8.04±1.76 mM	p < 0.01
Vitamin D (25-OH)	41.8±14.2 ng/mL	51.5±10.5 mg/mL	p < 0.01

Significance was calculated using a paired t-test, two-tailed. Hs-CRP, high-sensitivity C-reactive protein. HOMA-IR, homeostasis model assessment-estimated insulin resistance, calculated based on fasting insulin and fasting glucose (fasting insulin in mIU/L times fasting glucose in mg/dL, divided by 405.45). TG:HDL ratio, serum triglyceride-to-high-density-lipoprotein ratio. Vitamin D was measured as 25-hydroxycholecalciferol. Post-treatment tests were taken at the conclusion of the 9-month protocol for each patient, as described in the text. NS, not significant at p < 0.05.