Table 2.

Developmental Quotients and subscale scores at 24 months of age and Intelligence Quotients and subtest scores at 48 months of age in the two groups of patients with different initial treatment regimen.

	Low (10-12.5 μg/kg/day)	High (12.6-15 μg/kg/day)	Between-Group Difference (95% CI)	P
Age 24 months
Number of patients	28	27
Developmental quotient	100.6 ± 15.5	96.9 ± 16.6	3.8 (-4.9 to 12.4)	0.39
Subscale A	112.1 ± 21.4	109.1 ± 23.3	3 (-9.1 to 15.1)	0.62
Subscale B	100.5 ± 20.7	93.3 ± 25.3	7.2 (-5.3 to 19.7)	0.26
Subscale C	90.6 ± 19.7	87.7 ± 21.7	2.8 (-8.4 to 14)	0.61
Subscale D	105.4 ± 13.5	100.7 ± 17.5	4.7 (-3.8 to 13.1)	0.27
Subscale E	105.0 ± 14.9	102.4 ± 15.4	2.6 (-5.6 to 10.7)	0.53
Age 48 months
Number	24	21
Total Intelligence Quotient	104.2 ± 11.4	101.0 ± 20.3	3.1 (-6.6 to 12.8)	0.54
Verbal Intelligence Quotient	103.9 ± 11.5	98.7 ± 15.1	5.2 (-2.8 to 13.3)	0.20
Performance Intelligence Quotient	105.3 ± 10.4	100.3 ± 19.8	5 (-4.3 to 14.3)	0.31
Processing Speed Quotient	99.2 ± 13.1	97.1 ± 18.3	2.1 (-7.4 to 11.5)	0.67
Information	10.2 ± 2.3	9.1 ± 3.3	1.1 (-0.6 to 2.8)	0.21
Vocabulary	11.5 ± 2.4	10.2 ± 2.6	1.3 (-0.3 to 2.8)	0.10
Word Reasoning	10.3 ± 3.1	10.1 ± 2.8	0.2 (-1.6 to 2)	0.82
Block Design	9.7 ± 2.2	8.6 ± 3.6	1.1 (-0.6 to 2.9)	0.22
Matrix Reasoning	10.7 ± 2.6	11.6 ± 3.6	-0.9 (-2.8 to 1)	0.35
Picture Concepts	11.5 ± 2.8	10.0 ± 3.2	1.5 (-0.2 to 3.2)	0.10
Symbol Search	10.6 ± 2.6	9.5 ± 3.4	1.1 (-0.7 to 3)	0.22
Coding	9.1 ± 2.5	9.6 ± 3.7	-0.5 (-2.4 to 1.4)	0.60

Data are expressed as mean ± standard deviation.