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. 2022 Sep 16;10:e13992. doi: 10.7717/peerj.13992

Table 1. Characteristic of the included studies.

Studies Participants L carnitine dosage Intervention Comparison Duration of intervention
(El Sharkwy & Sharaf El-Din, 2019) Intervention, n = 140 Control, n = 140 3 g LC daily 150 mg/day CC plus oral LC 3g and metformin 850 mg (1 tablet daily) 150 mg/d CC plus metformin and placebo capsules 12 weeks
(El Sharkwy & Abd El Aziz, 2019) Intervention, n = 82 Control, n = 82 3 g LC daily 150 mg/day of CC plus 3 g of oral LC daily, and placebo sachets 150 mg/day of CC from day 3 until day 7 of the menstrual cycle plus 600 mg of oral N-acetylcysteine three times daily, and a placebo capsule 12 weeks
(Ismail et al., 2014) Intervention, n = 85 Control, n = 85 3 g LC daily 250 mg CC from day three until day seven of the cycle plus LC 3 g daily 250 mg CC with placebo 12 weeks
(Jamilian et al., 2017) Intervention, n = 30 Control, n = 30 250 mg LC 250 mg carnitine supplements Placebos (cellulose) 12 weeks
(Jamilian et al., 2019a) Intervention, n = 26 Control, n = 27 1,000 mg LC daily LC 1,000 mg/d plus 200 mg/d chromium as chromium picolinate Placebo 12 weeks
(Jamilian et al., 2019b) Intervention, n = 27 Control, n = 27 1,000 mg LC daily 200 µg/day chromium picolinate plus 1,000 mg/day LC Placebo (starch) 12 weeks
(Samimi et al., 2016) Intervention, n = 30 Control, n = 30 250 mg LC 250 mg LC (capsule range 237–275 mg) Placebo (cellulose) 12 weeks
(Talari et al., 2019) Intervention, n = 30 Control, n = 30 250 mg LC daily 250 mg/day of LC Placebo 12 weeks
(Kortam, Abdelrahman & Fateen, 2020) Intervention, n = 47 Control, n = 47 3g LC daily Oral CC (50 mg tablet, two times per day) plus oral LC supplementation (1 g tablet, three times per day) Oral CC only (50 mg tablet, two times per day). Not stated