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Roles of cytokine and chemokines on tumor MDSCs.
| Tumor | Cytokines/Signaling pathways | Functions | Ref |
|---|---|---|---|
|
BC
BC ESCC Melanoma |
BCC-Ex/CXCR4 BCC-Ex/STAT3 IL-6 CCR5 |
To increase MDSC and inhibit T cells To promote MDSC expansion To regulate the activation of MDSC To inhibit immune activity |
(27) (46) (44) (12) |
BC, Breast cancer; ESCC, Esophageal squamous cell carcinoma.
