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. 2022 Aug 16;99(7):e650–e659. doi: 10.1212/WNL.0000000000200771

Figure 1. Instrument Selection for Antidiabetic Drug Classes.

Figure 1

Black line represents DNA strand, and raised box represents the target gene region. Wedges represent specific genetic variants (SNVs). Disappearing of wedges indicates the exclusion of SNVs. DPP-4 inhibitors = dipeptidyl peptidase 4 inhibitors; GLP-1 analogues = glucagon-like peptide 1 analogues; SGLT2 inhibitors = sodium-glucose cotransporter 2 inhibitors; SNVs = single-nucleotide variations; TZD = thiazolidinediones; UKB = UK Biobank.