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. 2022 Sep 19;194(36):E1233–E1242. doi: 10.1503/cmaj.220892

Table 1:

Baseline characteristics of clients in safer opioid supply program and matched unexposed group

Characteristic No. (%)* of clients in SOS program at LIHC (n = 82) No. (%)* of matched unexposed individuals (n = 303; weighted n = 82) Weighted standardized difference
Age, yr; mean ± SD 40.8 ± 10.6 40.6 ± 5.5 0.01
Male sex 33 (40.2) 33.0 (40.2) 0.00
Income quintile
 1 (lowest) 57 (69.5) 57.0 (69.5) 0.00
 2 12 (14.6) 12.0 (14.6) 0.00
 3 9 (11.0) 9.0 (11.0) 0.00
 4§ ≤ 5 ≤ 5 0.00
 5 (highest)§ ≤ 5 ≤ 5 0.00
Eligible for public drug benefits 71 (86.6) 71 (86.6) 0.00
Diagnosis of HIV 28 (34.1) 6.3 (7.6) 0.69
Diagnosis of hepatitis C 57 (69.5) 20.8 (25.3) 0.99
Previous mental health–related or substance use hospital visit (1 yr) 20 (24.4) 15.0 (18.3) 0.15
 Anxiety disorders§ ≤ 5 ≤ 5 < 0.10
 Deliberate self-harm§ ≤ 5 ≤ 5 < 0.10
 Mood disorder§ 0 (0.00) ≤ 5 > 0.10
 Schizophrenia and other psychotic disorders§ ≤ 5 ≤ 5 < 0.10
 Substance use disorders 15 (18.3) 7.8 (9.5) 0.26
 Other§ ≤ 5 ≤ 5 < 0.10
ED visit or hospital admission for opioid toxicity (1 yr) 7 (8.5) 7.0 (8.5) 0.00
Inpatient hospital admission for any infection (1 yr) 23 (28.0) 9.3 (11.3) 0.43
 Infective endocarditis§ ≤ 5 ≤ 5 0.00
 Skin and soft-tissue infection§ 15 (18.3) ≤ 5 > 0.10
 Osteomyelitis, septic arthritis or spinal infection 9 (11.0) 7.3 (8.8) 0.07
Dispensed opioid agonist therapy (1 yr) 50 (61.0) 50.0 (61.0) 0.00
Dispensed methadone
 Past 30 days 25 (30.5) 34.8 (42.4) 0.25
 Past 365 days 42 (51.2) 41.3 (50.3) 0.02
 Past 5 years 60 (73.2) 63.5 (77.4) 0.10
Dispensed buprenorphine-naloxone
 Past 30 days 6 (7.3) 5.5 (6.7) 0.02
 Past 365 days 15 (18.3) 10.3 (12.5) 0.16
 Past 5 years 23 (28.0) 18.5 (22.6) 0.13
Dispensed immediate-release hydromorphone (90 d) 28 (34.1) 7.0 (8.5) 0.66
Dispensed long-acting hydromorphone (90 d)§ 8 (9.8) ≤ 5 > 0.10
Dispensed any opioid (90 d) 52 (63.4) 54.5 (66.5) 0.06
Dispensed benzodiazepines (30 d)§ ≤ 5 7.0 (8.5) > 0.10
No. of physician visits (1 yr), mean ± SD 24.50 ± 22.45 24.96 ± 10.15 0.02
No. of emergency department visits (1 yr), mean ± SD 3.28 ± 3.36 2.23 ± 2.54 0.25
No. of inpatient hospital admissions (1 yr), mean ± SD 0.95 ± 1.34 0.42 ± 0.57 0.44

Note: ED = emergency department, LIHC = London InterCommunity Health Centre, SD = standard deviation, SOS = safer opioid supply.

*

Unless otherwise indicated.

Counts and standardized differences weighted on number of unexposed individuals matched to each client in SOS program.

Matching criteria.

§

Censored according to privacy requirements for cell sizes smaller than 6. Accordingly, weighted standardized differences are suppressed to prevent residual disclosure.

Can be ED visit or inpatient stay in a mental health hospital or a mental health bed in an acute hospital.