Table 2. Characteristics of the patients included in the additional analysis, and results of the additional analysis for the primary and secondary outcomes.
| Salvage | Amputation | P-values | |
|---|---|---|---|
| Patients | 24 | 5 | |
| Age (years) | 48.6 (7–73) | 37.4 (23–47) | |
| Sex (M:F) | 21:3 | 4:1 | |
| OTA-OFC score | 10.1 (7–14) | 14.6 (14–15) | |
| Pre-operative LEFS | 79.8 (78–80) | 80.0 (80) | |
| Post-operative LEFS | 50.4 (19–80) | 46.4 (33–61) | 0.686 |
| SF-8 | |||
| Physical functioning | 41.7 | 38.4 | 0.645 |
| Role–physical | 42.2 | 35.7 | 0.296 |
| Bodily pain | 49 | 38.7 | 0.022* |
| General health | 51.9 | 46.3 | 0.085 |
| Vitality | 51.7 | 45.1 | 0.036* |
| Social functioning | 45 | 37.7 | 0.131 |
| Role emotional | 44.9 | 36.9 | 0.073 |
| Mental health | 48.4 | 36.3 | 0.005* |
| Physical component summary | 44 | 39.9 | 0.194 |
| Mental component summary | 48.2 | 38.2 | 0.012* |
| Number of operations | 4.3 (2–8) | 2.6 (2–3) | 0.023* |
| Infection rate (%) | 41.6 | 40.0 | 0.945 |
| Rate of change in employment (%) | 16.7 | 0.0 | 0.200 |
Additional analysis was performed after excluding patients with contralateral leg injuries, pelvic ring or acetabular fractures, and pre-injury LEFS scores of <77.
* indicates a significant difference. Data are presented as mean (range).
LEFS, lower extremity functional scale; OTA-OFC, Orthopedic Trauma Association Open Fracture Classification; SF-8, Short-Form 8