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. 2022 Sep 19;21(1):447–477. doi: 10.1007/s10311-022-01509-7

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The use of metal–organic frameworks in bioapplications faces some limitations, e.g., the high toxicity of synthetic components, the high toxicity of chemical reagents, and the unrecyclable preparation materials of metal–organic frameworks. In the most fundamental sense, metal–organic frameworks are porous polymeric materials formed by linking metal ions with organic bridging ligands. By constructing metal–organic frameworks from cyclodextrin and biocompatible metal ions, the limitations of metal–organic frameworks in bioapplications can be overcome. Methods for producing cyclodextrin-based metal–organic frameworks include vapor diffusion, microwave-assisted, hydro/solvothermal, and ultrasound-assisted. Food, anticritical, drug delivery, sensors, adsorbents, gas separation, and membranes are some of the applications for cyclodextrin-based metal–organic frameworks. MOFs refers to metal–organic frameworks, and CD-MOFs refers to cyclodextrin-based metal–organic frameworks