Table 2.

Summary of Commonly Used Oral Onychomycosis Medications

Medication	Dosing, Fingernails	Dosing, Toenails	Mycologic Cure Rate (%), Fingernails	Mycologic Cure Rate (%), Toenails	Complete Cure Rate (%), Fingernails	Complete cure Rate (%), Toenails	US FDA Approval
Terbinafine	250 mg daily for 6 weeks	250 mg daily for 12 weeks	79	70	59	38	Yes
Itraconazole	200 mg twice daily for 1 week separated by 3 weeks of washout for 2 treatment pulses	200 mg daily for 12 weeks	61	54	47	14	Yes
Fluconazole	150 mg weekly for 6–9 months	150 mg weekly for 12–18 months	NR	47–62	NR	37–48	No

Abbreviations: FDA, Food and Drug Administration; NR, not reported; US, United States.